Patagonia is a small town 12 miles southwest of Sonoita. Make sure to stop in at the Gathering Grounds coffee shop for a good cup of coffee, ice cream or a snack. 319 McKeown Ave.
The Duquesne House Bed & Breakfast: Locals recommend this small B&B in Patagonia. It is an historic adobe and former boarding house that was built in 1898. You might stay here and then explore the wineries near Sonoita.