Florence has many hotel options. Our top choice is the:
Il Tornabuoni Hotel: I have stayed at this hotel three times in the past when it was L’Hotel Tornabuoni Beaacci. It is well-located at Tornabuoni 3 where you can easily walk to nearby stores, restaurants, historic sites and museums. It used to be on one floor of an office building/old palazzo. Now under new management by AG Hotels, they have taken over a second floor and have added a number of new rooms, restaurant and have completed a total remodel. They also have a roof garden and terrace. I am excited to try it on my next visit.
Other hotel properties getting good press for design or comfort include Riva Lofts, Gallery Hotel Art, Relais Modern, Continentale, Hotel Torre Guelfa, Gran Hotel Villa Cora, Residence Hilde, El Salviatino and JK Place Firenze. The Villa Medici is another luxury option where I stayed on my first trip years ago.