Paso Robles has some great hotel options:
Orchard Hill Farm: I loved this small 3 bedroom inn/B&B in the heart of the wineries. The Garden room was a large suite with attractive furnishings, great bedding and a huge bath. The breakfasts were outstanding. They have a trained chef who comes in on weekends. The croissant with greens, a poached egg and prosciutto was wonderful as was the egg dish with vegetables the next morning. The owners, Deborah and Doug Thomsen, were so helpful in making tasting reservations and suggesting what wineries to visit. This was one of the best B&B experiences I have had!!!
Hotel Cheval: A beautiful luxury boutique hotel in the center of Downtown Paso Robles. 1021 Pine.
Justin Vineyards & Winery: For a true wine country experience, Justin is a excellent winery that has a well-known restaurant that is open for lunch and dinner. They also have a small Inn at the winery with four suites where you can stay and enjoy the beautiful countryside.
Another option is the Refugio which has two suites and offers cooking classes onsite. It is owned by tw0 well-known cookbook authors and is a short distance from town on Barley Grain Rd.
Comus House is a four-room B&B that is on the grounds of Denner Winery, recommended by The New Yorker.