St. Louis has some very good options for lodging.
I really enjoyed staying at the The Fleur-de-Lys Mansion which is a luxury B&B located in a 19th century mansion. The four guest rooms are lovely as are the living and dining room downstairs. The staff is excellent and the breakfast really great. I highly recommend this property and would definitely stay again on future trips. Jerilyn & Gary Sadler are the owners and innkeepers. 3500 Russell Blvd.
The Hotel Ignacio, at 3411 Olive St., is a boutique hotel that has gotten some good reviews and press.
Chase Park Plaza: Along Kingshighway in the Central West End, the Chase Park Plaza has been an institution in St. Louis since the 1920’s. You can easily walk to restaurants, shopping and bars plus you are across from Forest Park where you can explore the Art Museum and other venues.
Union Station Hotel, 1820 Market St.: This is an historic property in the headhouse of the train station that opened in 1894. The train station was restored in 1985 with a new 539-room hotel, shopping mall, restaurants and food court.
Also getting a great review is the Moonrise Hotel, a hip, boutique hotel in the Delmar Loop area. 6177 Delmar.